The NUTRIGENETICS panel of Genus Biotech evaluates the genetic predisposition to develop forms of intolerance towards different foods. In particular, we analyze polymorphisms associated with genes implicated in the predisposition to obesity (APOA2, APOA5 and FTO, obesity risk), in the metabolism of lactose (MCM6, hypolactasia) and in the metabolism of HISTAMINE (DAO). In addition, we offer a quick and reliable test for the determination of HLA-D haplotypes that increase the risk of developing gluten intolerance.
Celiac disease
Thanks to a simple and non-invasive DNA sampling, it is possible to determine the genetic predisposition to develop celiac disease, a gluten intolerance that causes inflammation of the small intestine with disabling consequences for the organism. Genus Biotech offers a fast and reliable genotyping service for the HLA locus to evaluate the presence of DQ2 / DQ8 haplotypes that modify individual susceptibility to celiac disease.
Lactose intolerance
Lactose intolerance (or hypolactasia) is defined as the inability to break down lactose, the main sugar found in milk. The deficiency or absence of the lactase enzyme causes the accumulation of lactose in the intestinal lumen where, thanks to the bacterial flora, it ferments, often causing discomfort of various sizes in the stomach and intestine. In Europe, approximately 90% of hypolactasia cases are due to a polymorphism present in the MCM6 gene that regulates the expression (and functioning) of lactase. Genus Biotech has developed a fast, reliable and inexpensive MCM6 polymorphism genotyping system.
Intolerance/obesity risk
With the analysis of polymorphisms it is possible to verify the predisposition to obesity and assess the tendency to develop intolerances towards substances that can cause pseudoallergic reactions, such as histamine. The TEST offered by Genus Biotech allows to reveal the presence of these allelic variants, in support of the definition of food plans adapted to your needs.